SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation
SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation
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Author / Creator
Zeng, Juan , Jiang, Manxi , Wu, Xinghan , Diao, Feiyang , Qiu, Danhong , Hou, Xiaojing , Wang, Haichao , Li, Ling , Li, Chunling , Ge, Juan , Liu, Jiayin , Ou, Xianghong and Wang, Qiang
Journal title
Language
English
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Contents
SIRT
4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse oocytes overexpressing
SIRT
4 are unable to completely progress through meiosis, showing the inadequate mitochondrial redistribution, lowered
ATP
content, elevated reactive oxygen sp...
Alternative Titles
Full title
SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation
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TN_cdi_crossref_primary_10_1111_acel_12789
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1111_acel_12789
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12789