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SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1111_acel_12789

SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

About this item

Full title

SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

Journal title

Aging cell, 2018-08, Vol.17 (4)

Language

English

Formats

More information

Scope and Contents

Contents

SIRT
4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse oocytes overexpressing
SIRT
4 are unable to completely progress through meiosis, showing the inadequate mitochondrial redistribution, lowered
ATP
content, elevated reactive oxygen sp...

Alternative Titles

Full title

SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1111_acel_12789

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1111_acel_12789

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.12789

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