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Lysophosphatidic acid receptor LPA 3 prevents oxidative stress and cellular senescence in Hutchinson...

Lysophosphatidic acid receptor LPA 3 prevents oxidative stress and cellular senescence in Hutchinson...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1111_acel_13064

Lysophosphatidic acid receptor LPA 3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome

About this item

Full title

Lysophosphatidic acid receptor LPA 3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome

Publisher

England

Journal title

Aging cell, 2020-01, Vol.19 (1), p.e13064

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Hutchinson-Gilford progeria syndrome (HGPS) is a rare laminopathy that produces a mutant form of prelamin A, known as Progerin, resulting in premature aging. HGPS cells show morphological abnormalities of the nuclear membrane, reduced cell proliferation rates, accumulation of reactive oxygen species (ROS), and expression of senescence markers. Lyso...

Alternative Titles

Full title

Lysophosphatidic acid receptor LPA 3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1111_acel_13064

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1111_acel_13064

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.13064

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