Targeting tumour-intrinsic N 7 -methylguanosine tRNA modification inhibits MDSC recruitment and impr...
Targeting tumour-intrinsic N 7 -methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy
About this item
Full title
Author / Creator
Liu, Haining , Zeng, Xuezhen , Ren, Xuxin , Zhang, Yifan , Huang, Manling , Tan, Li , Dai, Zihao , Lai, Jiaming , Xie, Wenxuan , Chen, Zebin , Peng, Sui , Xu, Lixia , Chen, Shuling , Shen, Shunli , Kuang, Ming and Lin, Shuibin
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Intrahepatic cholangiocarcinoma (ICC) exhibits very low response rate to immune checkpoint inhibitors (ICIs) and the underlying mechanism is largely unknown. We investigate the tumour immune microenvironment (TIME) of ICCs and the underlying regulatory mechanisms with the aim of developing new target to inhibit tumour growth and improve anti-progra...
Alternative Titles
Full title
Targeting tumour-intrinsic N 7 -methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1136_gutjnl_2022_327230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1136_gutjnl_2022_327230
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2022-327230
