The Synergistic Interaction of Interferon Types I and II Leads to Marked Reduction in Severe Acute R...
The Synergistic Interaction of Interferon Types I and II Leads to Marked Reduction in Severe Acute Respiratory Syndrome-Associated Coronavirus Replication and Increase in the Expression of mRNAs for Interferon-Induced Proteins
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Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Contents
Interferon (IFN)-α, -β and -γ have been shown to be only marginally effective against severe acute respiratory syndrome coronavirus (SARS-CoV) replication in Vero cell lines. We investigated the combination of type I IFNs (IFN-α or -β) and IFN-γ for antiviral activity and found that such combinations synergistically inhibited SARS-CoV replication i...
Alternative Titles
Full title
The Synergistic Interaction of Interferon Types I and II Leads to Marked Reduction in Severe Acute Respiratory Syndrome-Associated Coronavirus Replication and Increase in the Expression of mRNAs for Interferon-Induced Proteins
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TN_cdi_crossref_primary_10_1159_000098242
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1159_000098242
Other Identifiers
ISSN
0300-5526
E-ISSN
1423-0100
DOI
10.1159/000098242
