Assessing Pharmacokinetics of Different Doses of Fosfomycin in Laboratory Rats Enables Adequate Expo...
Assessing Pharmacokinetics of Different Doses of Fosfomycin in Laboratory Rats Enables Adequate Exposure for Pharmacodynamic Models
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Basel, Switzerland: S. Karger AG
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English
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Basel, Switzerland: S. Karger AG
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Contents
Fosfomycin has been the subject of numerous pharmacodynamic in vivo models in recent years. The present study set out to determine fosfomycin pharmacokinetics in laboratory rats to enable adequate dosing regimens in future rodent models. Fosfomycin was given intraperitoneally as single doses of 75, 200 and 500 mg/kg bodyweight to 4 Sprague-Dawley r...
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Assessing Pharmacokinetics of Different Doses of Fosfomycin in Laboratory Rats Enables Adequate Exposure for Pharmacodynamic Models
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TN_cdi_crossref_primary_10_1159_000357569
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1159_000357569
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ISSN
0031-7012
E-ISSN
1423-0313
DOI
10.1159/000357569