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Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of...

Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1159_000442976

Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of Acute Organ Failures during Sepsis

About this item

Full title

Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of Acute Organ Failures during Sepsis

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Journal of innate immunity, 2016-01, Vol.8 (2), p.211-220

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Purpose: We have recently shown that PCSK9 reduces the clearance of endotoxin and is therefore a critical regulator of the innate immune response during infection. However, plasma PCSK9 levels during human sepsis and their relationship to outcomes are not known. Our objective was to determine the relationship between plasma PCSK9 levels and the rat...

Alternative Titles

Full title

Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of Acute Organ Failures during Sepsis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1159_000442976

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1159_000442976

Other Identifiers

ISSN

1662-811X

E-ISSN

1662-8128

DOI

10.1159/000442976

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