Genome-Wide Association Study Links Autoimmune Addison’s Disease to Break of Central Tolerance
Genome-Wide Association Study Links Autoimmune Addison’s Disease to Break of Central Tolerance
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Author / Creator
Guillen, Maribel Aranda , Røyrvik, Ellen Christine , Eriksson, Daniel , Berger, Amund Holte , Landegren, Nils , Alvarez, Haydee Artaza , Hallgren, Åsa , Grytaas, Marianne Aardal , Ström, Sara , Bratland, Eirik , Botusan, Ileana , Oftedal, Bergithe , Breivik, Lars , Vaudel, Mark , Helgeland, Øyvind , Falorni, Alberto , Jørgensen, Anders , Hulting, Anna-Lena , Svartberg, Johan Bernhard , Ekwall, Olov , Fougner, Kristian , Hughes, Jeanette Wahlberg , Nedrebø, Bjørn , Dahlqvist, Per Mikael , Knappskog, Per Morten , Wolff, Anette Susanne Bøe , Bensing, Sophie , Johansson, Stefan , Kämpe, Olle and Husebye, Eystein Sverre
Journal title
Language
English
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Scope and Contents
Contents
Autoimmune Addison’s disease is the predominant cause of primary adrenal failure, and is highly heritable. The genetic background has remained poorly understood due to the low prevalence and complex inheritance of the disease. We performed a genome-wide association study, which identified nine independent risk loci (P < 5 × 10–8). In addition to no...
Alternative Titles
Full title
Genome-Wide Association Study Links Autoimmune Addison’s Disease to Break of Central Tolerance
Authors, Artists and Contributors
Author / Creator
Røyrvik, Ellen Christine
Eriksson, Daniel
Berger, Amund Holte
Landegren, Nils
Alvarez, Haydee Artaza
Hallgren, Åsa
Grytaas, Marianne Aardal
Ström, Sara
Bratland, Eirik
Botusan, Ileana
Oftedal, Bergithe
Breivik, Lars
Vaudel, Mark
Helgeland, Øyvind
Falorni, Alberto
Jørgensen, Anders
Hulting, Anna-Lena
Svartberg, Johan Bernhard
Ekwall, Olov
Fougner, Kristian
Hughes, Jeanette Wahlberg
Nedrebø, Bjørn
Dahlqvist, Per Mikael
Knappskog, Per Morten
Wolff, Anette Susanne Bøe
Bensing, Sophie
Johansson, Stefan
Kämpe, Olle
Husebye, Eystein Sverre
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1210_jendso_bvab048_338
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1210_jendso_bvab048_338
Other Identifiers
ISSN
2472-1972
E-ISSN
2472-1972
DOI
10.1210/jendso/bvab048.338
