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Pharmacokinetics of Boldine in Control and Mrp2-Deficient Rats

Pharmacokinetics of Boldine in Control and Mrp2-Deficient Rats

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_33549_physiolres_933520

Pharmacokinetics of Boldine in Control and Mrp2-Deficient Rats

About this item

Full title

Pharmacokinetics of Boldine in Control and Mrp2-Deficient Rats

Journal title

Physiological research, 2016-01, p.S489-S497

Language

English

Formats

More information

Scope and Contents

Contents

The aim of the present study was to describe the currently poorly understood pharmacokinetics (PK) of boldine in control rats (LW, Lewis rats), and Mrp2 transporter-deficient rats (TR-). Animals from the LW and TR- groups underwent a bolus dose study with 10 mg/kg of boldine applied either orally or intravenously in order to evaluate the major PK p...

Alternative Titles

Full title

Pharmacokinetics of Boldine in Control and Mrp2-Deficient Rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_33549_physiolres_933520

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_33549_physiolres_933520

Other Identifiers

ISSN

0862-8408

E-ISSN

1802-9973

DOI

10.33549/physiolres.933520

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