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Mechanistic Models of Inducible Synthetic Circuits for Joint Description of DNA Copy Number, Regulat...

Mechanistic Models of Inducible Synthetic Circuits for Joint Description of DNA Copy Number, Regulat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_3390_pr7030119

Mechanistic Models of Inducible Synthetic Circuits for Joint Description of DNA Copy Number, Regulatory Protein Level, and Cell Load

About this item

Full title

Mechanistic Models of Inducible Synthetic Circuits for Joint Description of DNA Copy Number, Regulatory Protein Level, and Cell Load

Journal title

Processes, 2019-02, Vol.7 (3), p.119

Language

English

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Scope and Contents

Contents

Accurate predictive mathematical models are urgently needed in synthetic biology to support the bottom-up design of complex biological systems, minimizing trial-and-error approaches. The majority of models used so far adopt empirical Hill functions to describe activation and repression in exogenously-controlled inducible promoter systems. However,...

Alternative Titles

Full title

Mechanistic Models of Inducible Synthetic Circuits for Joint Description of DNA Copy Number, Regulatory Protein Level, and Cell Load

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_3390_pr7030119

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_3390_pr7030119

Other Identifiers

ISSN

2227-9717

E-ISSN

2227-9717

DOI

10.3390/pr7030119

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