p53 reactivating small molecule PRIMA‑1 MET /APR‑246 regulates genomic instability in MDA‑MB‑231 cel...
p53 reactivating small molecule PRIMA‑1 MET /APR‑246 regulates genomic instability in MDA‑MB‑231 cells
About this item
Full title
Author / Creator
Publisher
Greece
Journal title
Language
English
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Publication information
Publisher
Greece
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More information
Scope and Contents
Contents
Pharmacological reactivation of tumor‑suppressor protein p53 has acted as a promising strategy for more than 50% of human cancers that carry a non‑functional mutant p53 (mutp53).
plays a critical role in preserving genomic integrity and DNA fidelity through numerous biological processes, including cell cycle arrest, DNA repair, senescence and ap...
Alternative Titles
Full title
p53 reactivating small molecule PRIMA‑1 MET /APR‑246 regulates genomic instability in MDA‑MB‑231 cells
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Record Identifier
TN_cdi_crossref_primary_10_3892_or_2022_8296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_3892_or_2022_8296
Other Identifiers
ISSN
1021-335X
E-ISSN
1791-2431
DOI
10.3892/or.2022.8296
