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Preclinical evaluation of an 111 In/ 225 Ac theranostic targeting transformed MUC1 for triple negati...

Preclinical evaluation of an 111 In/ 225 Ac theranostic targeting transformed MUC1 for triple negati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7150_thno_38236

Preclinical evaluation of an 111 In/ 225 Ac theranostic targeting transformed MUC1 for triple negative breast cancer

About this item

Full title

Preclinical evaluation of an 111 In/ 225 Ac theranostic targeting transformed MUC1 for triple negative breast cancer

Publisher

Australia

Journal title

Theranostics, 2020, Vol.10 (15), p.6946-6958

Language

English

Formats

Publication information

Publisher

Australia

More information

Scope and Contents

Contents

: Transformed MUC1 (tMUC1) is a cancer-associated antigen that is overexpressed in >90% of triple-negative breast cancers (TNBC), a highly metastatic and aggressive subtype of breast cancer. TAB004, a murine antibody targeting tMUC1, has shown efficacy for the targeted delivery of therapeutics to cancer cells. Our aim was to evaluate humanized TAB0...

Alternative Titles

Full title

Preclinical evaluation of an 111 In/ 225 Ac theranostic targeting transformed MUC1 for triple negative breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_7150_thno_38236

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7150_thno_38236

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.38236

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