Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates throu...
Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption
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Protein aggregation increases during aging and is a pathological hallmark of many age-related diseases. Protein homeostasis (proteostasis) depends on a core network of factors directly influencing protein production, folding, trafficking, and degradation. Cellular proteostasis also depends on the overall composition of the proteome and numerous env...
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Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption
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TN_cdi_crossref_primary_10_7554_eLife_86194_3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_86194_3
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2050-084X
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2050-084X
DOI
10.7554/eLife.86194.3