A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
About this item
Full title
A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
Author / Creator
Journal title
eLife, 2023-08, Vol.12
Language
English
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Scope and Contents
Contents
N
6
-methyladenosine (m
6
A) methylation of RNA by the methyltransferase complex (MTC), with core components including METTL3–METTL14 heterodimers and
Wilms’ tumor 1-associated protein
(WTAP), contributes to breast tumorigenesis, but the underlying regulatory mechanisms remain elusive. Here, we identify a novel cleaved form METTL3...
Alternative Titles
Full title
A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_7554_eLife_87283_3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_87283_3
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.87283.3
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