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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendriti...

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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendriti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_89319_4

Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis

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During tuberculosis (TB), migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the rapid development of protective T-cell-mediated immunity. However, the mechanisms involved in the delayed migration of DCs during TB are still poorly defined. Here, we found that infection of DCs...

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Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis

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TN_cdi_crossref_primary_10_7554_eLife_89319_4

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_89319_4

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ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.89319.4

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