A preclinical model of THC edibles that produces high-dose cannabimimetic responses
A preclinical model of THC edibles that produces high-dose cannabimimetic responses
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English
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No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ
9
-tetrahydrocannabinol (THC) and its intoxicating effects, mainly owing to the aversive response of rodents to THC that limits intake. Here, we developed a palatable THC formulation and an optimized access paradigm in mice to drive vo...
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A preclinical model of THC edibles that produces high-dose cannabimimetic responses
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TN_cdi_crossref_primary_10_7554_eLife_89867_3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_89867_3
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.89867.3