Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion an...
Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration
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Orexin signaling in the ventral tegmental area and substantia nigra promotes locomotion and reward processing, but it is not clear whether dopaminergic neurons directly mediate these effects. We show that dopaminergic neurons in these areas mainly express orexin receptor subtype 1 (Ox1R). In contrast, only a minor population in the medial ventral t...
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Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration
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TN_cdi_crossref_primary_10_7554_eLife_91716_4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_91716_4
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2050-084X
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2050-084X
DOI
10.7554/eLife.91716.4