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Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesi...

Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_91729_3

Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations

About this item

Full title

Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations

Journal title

eLife, 2024-04, Vol.12

Language

English

Formats

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Scope and Contents

Contents

Heterogeneity in endothelial cell (EC) sub-phenotypes is becoming increasingly appreciated in atherosclerosis progression. Still, studies quantifying EC heterogeneity across whole transcriptomes and epigenomes in both in vitro and in vivo models are lacking. Multiomic profiling concurrently measuring transcriptomes and accessible chromatin in the s...

Alternative Titles

Full title

Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_7554_eLife_91729_3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_91729_3

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.91729.3

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