Conformational dynamics of a nicotinic receptor neurotransmitter site
Conformational dynamics of a nicotinic receptor neurotransmitter site
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Full title
Conformational dynamics of a nicotinic receptor neurotransmitter site
Author / Creator
Journal title
eLife, 2024-12, Vol.13
Language
English
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Scope and Contents
Contents
Agonists enhance receptor activity by providing net-favorable binding energy to active over resting conformations, with efficiency (η) linking binding energy to gating. Previously, we showed that in nicotinic receptors, η-values are grouped into five structural pairs, correlating efficacy and affinity within each class, uniting binding with alloste...
Alternative Titles
Full title
Conformational dynamics of a nicotinic receptor neurotransmitter site
Authors, Artists and Contributors
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Record Identifier
TN_cdi_crossref_primary_10_7554_eLife_92418_4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_92418_4
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.92418.4
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