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Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aerug...

Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aerug...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_98851_3

Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice

About this item

Full title

Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice

Journal title

eLife, 2025-04, Vol.13

Language

English

Formats

More information

Scope and Contents

Contents

Pseudomonas aeruginosa (PA) is an opportunistic, frequently multidrug-resistant pathogen that can cause severe infections in hospitalized patients. Antibodies against the PA virulence factor, PcrV, protect from death and disease in a variety of animal models. However, clinical trials of PcrV-binding antibody-based products have thus far failed to d...

Alternative Titles

Full title

Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_7554_eLife_98851_3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_98851_3

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.98851.3

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