IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation
IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation
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BioMed Central
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Language
English
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BioMed Central
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Background: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known about how these extracellular factors instruct innate immune cell epigenomes to engage specific differentiation states. Human monocytes differentiate under inflammatory conditions into effec...
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Full title
IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation
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TN_cdi_csuc_recercat_oai_recercat_cat_2072_314565
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_csuc_recercat_oai_recercat_cat_2072_314565
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ISSN
1474-760X
DOI
10.1186/s13059-015-0863-2
