Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose re...
Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response
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Publisher
Public Library of Science (PLoS)
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Language
English
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Publisher
Public Library of Science (PLoS)
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Contents
Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. The aim of this study is to analyze methadone dosage in responder and nonresponder patients considering pharmacogenetic an...
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Full title
Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response
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TN_cdi_csuc_recercat_oai_recercat_cat_2072_315360
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_csuc_recercat_oai_recercat_cat_2072_315360
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0019527
