Understanding the Connetion between Epigenetic DNA Methylation and Nucleosome Positioning from Compu...
Understanding the Connetion between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations
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Public Library of Science (PLoS)
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English
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Public Library of Science (PLoS)
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Cytosine methylation is one of the most important epigenetic marks that regulate the process of gene expression. Here, we have examined the effect of epigenetic DNA methylation on nucleosomal stability using molecular dynamics simulations and elastic deformation models. We found that methylation of CpG steps destabilizes nucleosomes, especially whe...
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Understanding the Connetion between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations
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TN_cdi_csuc_recercat_oai_recercat_cat_2072_368026
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_csuc_recercat_oai_recercat_cat_2072_368026
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1553-734X
