Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane m...
Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A wide range of diseases have been shown to be influenced by the accumulation of senescent cells, from fibrosis to diabetes, cancer, Alzheimer’s and other age-related pathologies. Consistent with this, clearance of senescent cells can prolong healthspan and lifespan in in vivo models. This provided a rationale for developing a new class of drugs, c...
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Full title
Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker
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TN_cdi_doaj_primary_oai_doaj_org_article_0025965e081a437187edf55f3e63aa33
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0025965e081a437187edf55f3e63aa33
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-99852-2
