Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle forma...
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
About this item
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Author / Creator
Tabata, Keisuke , Prasad, Vibhu , Paul, David , Lee, Ji-Young , Pham, Minh-Tu , Twu, Woan-Ing , Neufeldt, Christopher J. , Cortese, Mirko , Cerikan, Berati , Stahl, Yannick , Joecks, Sebastian , Tran, Cong Si , Lüchtenborg, Christian , V’kovski, Philip , Hörmann, Katrin , Müller, André C. , Zitzmann, Carolin , Haselmann, Uta , Beneke, Jürgen , Kaderali, Lars , Erfle, Holger , Thiel, Volker , Lohmann, Volker , Superti-Furga, Giulio , Brügger, Britta , Bartenschlager, Ralf and Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Double membrane vesicles (DMVs) serve as replication organelles of plus-strand RNA viruses such as hepatitis C virus (HCV) and SARS-CoV-2. Viral DMVs are morphologically analogous to DMVs formed during autophagy, but lipids driving their biogenesis are largely unknown. Here we show that production of the lipid phosphatidic acid (PA) by acylglycerol...
Alternative Titles
Full title
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
Authors, Artists and Contributors
Author / Creator
Prasad, Vibhu
Paul, David
Lee, Ji-Young
Pham, Minh-Tu
Twu, Woan-Ing
Neufeldt, Christopher J.
Cortese, Mirko
Cerikan, Berati
Stahl, Yannick
Joecks, Sebastian
Tran, Cong Si
Lüchtenborg, Christian
V’kovski, Philip
Hörmann, Katrin
Müller, André C.
Zitzmann, Carolin
Haselmann, Uta
Beneke, Jürgen
Kaderali, Lars
Erfle, Holger
Thiel, Volker
Lohmann, Volker
Superti-Furga, Giulio
Brügger, Britta
Bartenschlager, Ralf
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_004cd836b49b455dbee0043b2c9d12d0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_004cd836b49b455dbee0043b2c9d12d0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27511-1
