Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects t...
Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine
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Author / Creator
He, Xuemei , Hong, Weiqi , Yang, Jingyun , Lei, Hong , Lu, Tianqi , He, Cai , Bi, Zhenfei , Pan, Xiangyu , Liu, Yu , Dai, Lunzhi , Wang, Wei , Huang, Canhua , Deng, Hongxin and Wei, Xiawei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mesenchymal stem cell (MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases, but its underlying mechanism has not been fully understood. Dead cells, including apoptotic cells have immunomodulatory properties. It has been repeatedly reported that the proportion of nonviable MSCs in a MSC therapeutic preparation varie...
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Full title
Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine
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TN_cdi_doaj_primary_oai_doaj_org_article_007e3a9b0c0e4ce0b6c20b2002a41625
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_007e3a9b0c0e4ce0b6c20b2002a41625
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ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-021-00688-z
