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SVEP1 is an endogenous ligand for the orphan receptor PEAR1

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00a5662500fa4216a282bb3c8ddfa931

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

About this item

Full title

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-02, Vol.14 (1), p.850-18, Article 850

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (SVEP1) is an extracellular matrix protein that causally promotes vascular disease and associates with platelet reactivity in humans. Here, using a human genomic and proteomic approach, we identify a high affinity, disease-relevant, and potentially targetable interaction bet...

Alternative Titles

Full title

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_00a5662500fa4216a282bb3c8ddfa931

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00a5662500fa4216a282bb3c8ddfa931

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-36486-0

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