Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA
Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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APOBEC1 (A1) enzymes are cytidine deaminases involved in RNA editing. In addition to this activity, a few A1 enzymes have been shown to be active on single stranded DNA. As two human ssDNA cytidine deaminases APOBEC3A (A3A), APOBEC3B (A3B) and related enzymes across the spectrum of placental mammals have been shown to introduce somatic mutations in...
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Full title
Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA
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TN_cdi_doaj_primary_oai_doaj_org_article_00a6046ee2244f53afae207b0b6b99ea
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00a6046ee2244f53afae207b0b6b99ea
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-019-6216-x
