Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage...
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway
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Xu, Xin , Gao, Weiwei , Li, Lei , Hao, Jiheng , Yang, Bin , Wang, Tao , Li, Long , Bai, Xuesong , Li, Fanjian , Ren, Honglei , Zhang, Meng , Zhang, Liyong , Wang, Jiyue , Wang, Dong , Zhang, Jianning and Jiao, Liqun
Publisher
London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Cerebral ischemia-reperfusion (I/R) injury is a major cause of early complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in patients with acute ischemic stroke (AIS). Recent studies indicate that modulating microglia/macrophage polarization and subsequent inflammatory response may be a potential adjunct t...
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Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_00b845876d644362bf81462f39b6975a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00b845876d644362bf81462f39b6975a
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-021-02174-3