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TFIP11 promotes replication fork reversal to preserve genome stability

TFIP11 promotes replication fork reversal to preserve genome stability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00f7c422a4dd4430b23246b18637fc0c

TFIP11 promotes replication fork reversal to preserve genome stability

About this item

Full title

TFIP11 promotes replication fork reversal to preserve genome stability

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-02, Vol.15 (1), p.1262-1262, Article 1262

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Replication fork reversal, a critical protective mechanism against replication stress in higher eukaryotic cells, is orchestrated via a series of coordinated enzymatic reactions. The Bloom syndrome gene product, BLM, a member of the highly conserved RecQ helicase family, is implicated in this process, yet its precise regulation and role remain poor...

Alternative Titles

Full title

TFIP11 promotes replication fork reversal to preserve genome stability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_00f7c422a4dd4430b23246b18637fc0c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00f7c422a4dd4430b23246b18637fc0c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-45684-3

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