Sequence variants with large effects on cardiac electrophysiology and disease
Sequence variants with large effects on cardiac electrophysiology and disease
About this item
Full title
Author / Creator
Norland, Kristjan , Sveinbjornsson, Gardar , Thorolfsdottir, Rosa B. , Davidsson, Olafur B. , Tragante, Vinicius , Rajamani, Sridharan , Helgadottir, Anna , Gretarsdottir, Solveig , van Setten, Jessica , Asselbergs, Folkert W. , Sverrisson, Jon Th , Stephensen, Sigurdur S. , Oskarsson, Gylfi , Sigurdsson, Emil L. , Andersen, Karl , Danielsen, Ragnar , Thorgeirsson, Gudmundur , Thorsteinsdottir, Unnur , Arnar, David O. , Sulem, Patrick , Holm, Hilma , Gudbjartsson, Daniel F. and Stefansson, Kari
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS complex in 12 leads, using 405,732 electrocardiograms from 81,192 Icelanders. We identify 190 associat...
Alternative Titles
Full title
Sequence variants with large effects on cardiac electrophysiology and disease
Authors, Artists and Contributors
Author / Creator
Sveinbjornsson, Gardar
Thorolfsdottir, Rosa B.
Davidsson, Olafur B.
Tragante, Vinicius
Rajamani, Sridharan
Helgadottir, Anna
Gretarsdottir, Solveig
van Setten, Jessica
Asselbergs, Folkert W.
Sverrisson, Jon Th
Stephensen, Sigurdur S.
Oskarsson, Gylfi
Sigurdsson, Emil L.
Andersen, Karl
Danielsen, Ragnar
Thorgeirsson, Gudmundur
Thorsteinsdottir, Unnur
Arnar, David O.
Sulem, Patrick
Holm, Hilma
Gudbjartsson, Daniel F.
Stefansson, Kari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_013cd3a5a1cd47ec9888561074de6288
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_013cd3a5a1cd47ec9888561074de6288
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12682-9
