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Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled Receptor

Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled Receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01492600aa0f409f8f890261727a14f9

Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled Receptor

About this item

Full title

Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled Receptor

Publisher

Switzerland: Frontiers Research Foundation

Journal title

Frontiers in molecular neuroscience, 2022-06, Vol.15, p.891537-891537

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Research Foundation

More information

Scope and Contents

Contents

Brain-derived Neurotrophic Factor (BDNF) binds to the TrkB tyrosine kinase receptor, which dictates the sensitivity of neurons to BDNF. A unique feature of TrkB is the ability to be activated by small molecules in a process called transactivation. Here we report that the brain neuropeptide oxytocin increases BDNF TrkB activity in primary cortical n...

Alternative Titles

Full title

Transactivation of TrkB Receptors by Oxytocin and Its G Protein-Coupled Receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_01492600aa0f409f8f890261727a14f9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01492600aa0f409f8f890261727a14f9

Other Identifiers

ISSN

1662-5099

E-ISSN

1662-5099

DOI

10.3389/fnmol.2022.891537

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