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Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells again...

Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells again...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_015396e342d8443aa4091f21f509b391

Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma

About this item

Full title

Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma

Publisher

Australia: John Wiley & Sons, Inc

Journal title

Clinical & Translational Immunology, 2024-01, Vol.13 (7), p.e1519-n/a

Language

English

Formats

Publication information

Publisher

Australia: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

CAR-T cells are being investigated as a novel immunotherapy for glioblastoma, but clinical success has been limited. We recently described fibroblast activation protein (FAP) as an ideal target antigen for glioblastoma immunotherapy, with expression on both tumor cells and tumor blood vessels. However, CAR-T cells targeting FAP have never been inve...

Alternative Titles

Full title

Endogenous bystander killing mechanisms enhance the activity of novel FAP‐specific CAR‐T cells against glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_015396e342d8443aa4091f21f509b391

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_015396e342d8443aa4091f21f509b391

Other Identifiers

ISSN

2050-0068

E-ISSN

2050-0068

DOI

10.1002/cti2.1519

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