Origin of the 3-methylglutaryl moiety in caprazamycin biosynthesis
Origin of the 3-methylglutaryl moiety in caprazamycin biosynthesis
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Caprazamycins are liponucleoside antibiotics showing bioactivity against Gram-positive bacteria including clinically relevant Mycobacterium tuberculosis by targeting the bacterial MraY-translocase. Their chemical structure contains a unique 3-methylglutaryl moiety which they only share with the closely related liposidomycins. Although the biosynthe...
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Full title
Origin of the 3-methylglutaryl moiety in caprazamycin biosynthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_0157637d322f4a4ab4f9c3206b4fc847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0157637d322f4a4ab4f9c3206b4fc847
Other Identifiers
ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-022-01955-6
