EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
About this item
Full title
Author / Creator
Oldrini, Barbara , Hsieh, Wan-Ying , Erdjument-Bromage, Hediye , Codega, Paolo , Carro, Maria Stella , Curiel-García, Alvaro , Campos, Carl , Pourmaleki, Maryam , Grommes, Christian , Vivanco, Igor , Rohle, Daniel , Bielski, Craig M. , Taylor, Barry S. , Hollmann, Travis J. , Rosenblum, Marc , Tempst, Paul , Blenis, John , Squatrito, Massimo and Mellinghoff, Ingo K.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Transport of macromolecules through the nuclear pore by importins and exportins plays a critical role in the spatial regulation of protein activity. How cancer cells co-opt this process to promote tumorigenesis remains unclear. The epidermal growth factor receptor (EGFR) plays a critical role in normal development and in human cancer. Here we descr...
Alternative Titles
Full title
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
Authors, Artists and Contributors
Author / Creator
Hsieh, Wan-Ying
Erdjument-Bromage, Hediye
Codega, Paolo
Carro, Maria Stella
Curiel-García, Alvaro
Campos, Carl
Pourmaleki, Maryam
Grommes, Christian
Vivanco, Igor
Rohle, Daniel
Bielski, Craig M.
Taylor, Barry S.
Hollmann, Travis J.
Rosenblum, Marc
Tempst, Paul
Blenis, John
Squatrito, Massimo
Mellinghoff, Ingo K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_015fa09cb6784ac18a7db7bbdca85e1c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_015fa09cb6784ac18a7db7bbdca85e1c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02185-w
