Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, geneticall...
Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia
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Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
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Publication information
Publisher
England: The Company of Biologists Ltd
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Scope and Contents
Contents
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic cancer derived from the malignant transformation of T-cell progenitors. Outcomes remain poor for T-ALL patients who have either primary resistance to standard-of-care chemotherapy or disease relapse. Notably, there are currently no targeted therapies available in T-ALL. This l...
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Full title
Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_016e78ba93fb47f4bb242fee2e420e97
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_016e78ba93fb47f4bb242fee2e420e97
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.040931
