p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer
p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The p63 protein is a master regulatory transcription factor that plays crucial roles in cell differentiation, adult tissue homeostasis, and chromatin remodeling, and its dysregulation is associated with genetic disorders, physiological and premature aging, and cancer. The effects of p63 are carried out by two main isoforms that regulate cell prolif...
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p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_01bb9c2335294ed08740ca86259bafd2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01bb9c2335294ed08740ca86259bafd2
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells14010043