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p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer

p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01bb9c2335294ed08740ca86259bafd2

p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer

About this item

Full title

p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2025-01, Vol.14 (1), p.43

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The p63 protein is a master regulatory transcription factor that plays crucial roles in cell differentiation, adult tissue homeostasis, and chromatin remodeling, and its dysregulation is associated with genetic disorders, physiological and premature aging, and cancer. The effects of p63 are carried out by two main isoforms that regulate cell prolif...

Alternative Titles

Full title

p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_01bb9c2335294ed08740ca86259bafd2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01bb9c2335294ed08740ca86259bafd2

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells14010043

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