SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stabilit...
SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability
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Author / Creator
Li, Lei , Shi, Lan , Yang, Shangda , Yan, Ruorong , Zhang, Di , Yang, Jianguo , He, Lin , Li, Wanjin , Yi, Xia , Sun, Luyang , Liang, Jing , Cheng, Zhongyi , Shi, Lei , Shang, Yongfeng and Yu, Wenhua
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Although SIRT7 is a member of sirtuin family proteins that are described as NAD
+
-dependent class III histone deacetylases, the intrinsic enzymatic activity of this sirtuin protein remains to be investigated and the cellular function of SIRT7 remains to be explored. Here we report that SIRT7 is an NAD
+
-dependent histone desuccinylase...
Alternative Titles
Full title
SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability
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TN_cdi_doaj_primary_oai_doaj_org_article_01d2d2142bd449bf920ece34e4a0cc1c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01d2d2142bd449bf920ece34e4a0cc1c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12235
