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The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease

The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01f9780565ff47d7966f8adea0d65f6b

The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease

About this item

Full title

The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-06, Vol.15 (1), p.4775-19, Article 4775

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The metal ion transporter SLC39A8 is associated with physiological traits and diseases, including blood manganese (Mn) levels and inflammatory bowel diseases (IBD). The mechanisms by which SLC39A8 controls Mn homeostasis and epithelial integrity remain elusive. Here, we generate
Slc39a8
intestinal epithelial cell-specific-knockout (
Slc39a...

Alternative Titles

Full title

The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_01f9780565ff47d7966f8adea0d65f6b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_01f9780565ff47d7966f8adea0d65f6b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-49049-8

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