Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate...
Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation
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Zheng, Junhao , Wang, Yali , Tao, Liye , Cai, Jingwei , Shen, Zefeng , Liu, Yang , Pan, Haoyu , Li, Shihao , Ruan, Yeling , Chen, Tianyi , Ye, Zhengtao , Lin, Kainan , Sun, Yin , Xu, Junjie and Liang, Xiao
Publisher
London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood. Methods Circular RNA hsa_circ_0001681 (termed Circ-RAPGEF5 hereafter) was identified by circular RNA sequencing from 19 pairs...
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Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation
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TN_cdi_doaj_primary_oai_doaj_org_article_022d9e577d11405596a4e69052826ee3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_022d9e577d11405596a4e69052826ee3
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-023-02813-y