Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor...
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter
About this item
Full title
Author / Creator
Zhu, Yueming , Zou, Xianghui , Dean, Angela E. , Brien, Joseph O’ , Gao, Yucheng , Tran, Elizabeth L. , Park, Seong-Hoon , Liu, Guoxiang , Kieffer, Matthew B. , Jiang, Haiyan , Stauffer, Melissa E. , Hart, Robert , Quan, Songhua , Satchell, Karla J. F. , Horikoshi, Nobuo , Bonini, Marcelo and Gius, David
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Manganese superoxide dismutase (MnSOD) functions as a tumor suppressor; however, once tumorigenesis occurs, clinical data suggest MnSOD levels correlate with more aggressive human tumors, implying a potential dual function of MnSOD in the regulation of metabolism. Here we show, using in vitro transformation and xenograft growth assays that the MnSO...
Alternative Titles
Full title
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_024c2a17f581441ca1d27fe75c08a597
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_024c2a17f581441ca1d27fe75c08a597
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10352-4
