T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
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Author / Creator
Li, Fanlin , Zhang, Huihui , Wang, Wanting , Yang, Puyuan , Huang, Yue , Zhang, Junshi , Yan, Yaping , Wang, Yuan , Ding, Xizhong , Liang, Jie , Qi, Xinyue , Li, Min , Han, Ping , Zhang, Xiaoqing , Wang, Xin , Cao, Jiang , Fu, Yang-Xin and Yang, Xuanming
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The success of chimeric antigen receptor (CAR) T cells in treating B cell malignancies comes at the price of eradicating normal B cells. Even though T cell malignancies are aggressive and treatment options are limited, similar strategies for T cell malignancies are constrained by the severe immune suppression arising from bystander T cell aplasia....
Alternative Titles
Full title
T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_02c488a10011477f8b02989ecac19cbe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_02c488a10011477f8b02989ecac19cbe
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32092-8
