Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 recept...
Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 receptor and perturbation of cell-specific transcriptional programs
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Insulin secretion is impaired in individuals with cystic fibrosis (CF), contributing to high rates of CF-related diabetes (CFRD) and substantially increasing disease burden. To develop improved therapies for CFRD, better knowledge of pancreatic pathology in CF is needed. Glucagon like peptide-1 (GLP-1) from islet α cells potentiates insulin secreti...
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Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 receptor and perturbation of cell-specific transcriptional programs
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TN_cdi_doaj_primary_oai_doaj_org_article_02eecb3558cb4daeb1a5360a32a28b02
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_02eecb3558cb4daeb1a5360a32a28b02
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-76722-1
