BAD and KATP channels regulate neuron excitability and epileptiform activity
BAD and KATP channels regulate neuron excitability and epileptiform activity
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Cambridge: eLife Sciences Publications Ltd
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English
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Cambridge: eLife Sciences Publications Ltd
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Contents
Brain metabolism can profoundly influence neuronal excitability. Mice with genetic deletion or alteration of Bad (BCL-2 agonist of cell death) exhibit altered brain-cell fuel metabolism, accompanied by resistance to acutely induced epileptic seizures; this seizure protection is mediated by ATP-sensitive potassium (KATP) channels. Here we investigat...
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Full title
BAD and KATP channels regulate neuron excitability and epileptiform activity
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TN_cdi_doaj_primary_oai_doaj_org_article_0354aff8c3874c26813144fda6366778
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0354aff8c3874c26813144fda6366778
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.32721
