Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneupl...
Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
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Full title
Author / Creator
Springer, Simeon U , Chen, Chung-Hsin , Rodriguez Pena, Maria Del Carmen , Li, Lu , Douville, Christopher , Wang, Yuxuan , Cohen, Joshua David , Taheri, Diana , Silliman, Natalie , Schaefer, Joy , Ptak, Janine , Dobbyn, Lisa , Papoli, Maria , Kinde, Isaac , Afsari, Bahman , Tregnago, Aline C , Bezerra, Stephania M , VandenBussche, Christopher , Fujita, Kazutoshi , Ertoy, Dilek , Cunha, Isabela W , Yu, Lijia , Bivalacqua, Trinity J , Grollman, Arthur P , Diaz, Luis A , Karchin, Rachel , Danilova, Ludmila , Huang, Chao-Yuan , Shun, Chia-Tung , Turesky, Robert J , Yun, Byeong Hwa , Rosenquist, Thomas A , Pu, Yeong-Shiau , Hruban, Ralph H , Tomasetti, Cristian , Papadopoulos, Nickolas , Kinzler, Ken W , Vogelstein, Bert , Dickman, Kathleen G and Netto, George J
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
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More information
Scope and Contents
Contents
Current non-invasive approaches for detection of urothelial cancers are suboptimal. We developed a test to detect urothelial neoplasms using DNA recovered from cells shed into urine. UroSEEK incorporates massive parallel sequencing assays for mutations in 11 genes and copy number changes on 39 chromosome arms. In 570 patients at risk for bladder ca...
Alternative Titles
Full title
Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
Authors, Artists and Contributors
Author / Creator
Chen, Chung-Hsin
Rodriguez Pena, Maria Del Carmen
Li, Lu
Douville, Christopher
Wang, Yuxuan
Cohen, Joshua David
Taheri, Diana
Silliman, Natalie
Schaefer, Joy
Ptak, Janine
Dobbyn, Lisa
Papoli, Maria
Kinde, Isaac
Afsari, Bahman
Tregnago, Aline C
Bezerra, Stephania M
VandenBussche, Christopher
Fujita, Kazutoshi
Ertoy, Dilek
Cunha, Isabela W
Yu, Lijia
Bivalacqua, Trinity J
Grollman, Arthur P
Diaz, Luis A
Karchin, Rachel
Danilova, Ludmila
Huang, Chao-Yuan
Shun, Chia-Tung
Turesky, Robert J
Yun, Byeong Hwa
Rosenquist, Thomas A
Pu, Yeong-Shiau
Hruban, Ralph H
Tomasetti, Cristian
Papadopoulos, Nickolas
Kinzler, Ken W
Vogelstein, Bert
Dickman, Kathleen G
Netto, George J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_035e9fc0aa4749039ab3ee51913706ab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_035e9fc0aa4749039ab3ee51913706ab
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.32143
