Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation ind...
Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Selenoprotein P (SeP) is a major selenoprotein in serum predominantly produced in the liver. Excess SeP impairs insulin secretion from the pancreas and insulin sensitivity in skeletal muscle, thus inhibition of SeP could be a therapeutic strategy for type 2 diabetes. In this study, we examine the effect of sulforaphane (SFN), a phytochemical of bro...
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Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2
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TN_cdi_doaj_primary_oai_doaj_org_article_038aa5dfb13447abb55a8e8f2603a42f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_038aa5dfb13447abb55a8e8f2603a42f
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2399-3642
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2399-3642
DOI
10.1038/s42003-023-05449-y