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Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation ind...

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation ind...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_038aa5dfb13447abb55a8e8f2603a42f

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2

About this item

Full title

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2023-10, Vol.6 (1), p.1060-1060, Article 1060

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Selenoprotein P (SeP) is a major selenoprotein in serum predominantly produced in the liver. Excess SeP impairs insulin secretion from the pancreas and insulin sensitivity in skeletal muscle, thus inhibition of SeP could be a therapeutic strategy for type 2 diabetes. In this study, we examine the effect of sulforaphane (SFN), a phytochemical of bro...

Alternative Titles

Full title

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_038aa5dfb13447abb55a8e8f2603a42f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_038aa5dfb13447abb55a8e8f2603a42f

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-023-05449-y

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