Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using i...
Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
About this item
Full title
Author / Creator
Univ. of Texas MD Anderson Cancer Center, Houston, TX (United States) , Univ. of New Mexico, Albuquerque, NM (United States) , Houston Methodist Research Inst., Houston, TX (United States) , Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) , Dogra, Prashant , Adolphi, Natalie L. , Wang, Zhihui , Lin, Yu-Shen , Butler, Kimberly S. , Durfee, Paul N. , Croissant, Jonas G. , Noureddine, Achraf , Coker, Eric N. , Bearer, Elaine L. , Cristini, Vittorio and Brinker, C. Jeffrey
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The progress of nanoparticle (NP)-based drug delivery has been hindered by an inability to establish structure-activity relationships in vivo. Here, using stable, monosized, radiolabeled, mesoporous silica nanoparticles (MSNs), we apply an integrated SPECT/CT imaging and mathematical modeling approach to understand the combined effects of MSN size,...
Alternative Titles
Full title
Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
Authors, Artists and Contributors
Author / Creator
Univ. of New Mexico, Albuquerque, NM (United States)
Houston Methodist Research Inst., Houston, TX (United States)
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Dogra, Prashant
Adolphi, Natalie L.
Wang, Zhihui
Lin, Yu-Shen
Butler, Kimberly S.
Durfee, Paul N.
Croissant, Jonas G.
Noureddine, Achraf
Coker, Eric N.
Bearer, Elaine L.
Cristini, Vittorio
Brinker, C. Jeffrey
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_03c874c2055f48d9bf522fd89ec06520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_03c874c2055f48d9bf522fd89ec06520
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06730-z
