Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner
Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner
About this item
Full title
Author / Creator
Fazazi, Mohamed Reda , Doss, Prenitha Mercy Ignatius Arokia , Pereira, Resel , Fudge, Neva , Regmi, Aryan , Joly-Beauparlant, Charles , Akbar, Irshad , Yeola, Asmita Pradeep , Mailhot, Benoit , Baillargeon, Joanie , Grenier, Philippe , Bertrand, Nicolas , Lacroix, Steve , Droit, Arnaud , Moore, Craig S. , Rojas, Olga L. and Rangachari, Manu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
B cells and T cells collaborate in multiple sclerosis (MS) pathogenesis. IgH
[MOG]
mice possess a B cell repertoire skewed to recognize myelin oligodendrocyte glycoprotein (MOG). Here, we show that upon immunization with the T cell-obligate autoantigen, MOG
[35-55]
, IgH
[MOG]
mice develop rapid and exacerbated experimental autoim...
Alternative Titles
Full title
Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner
Authors, Artists and Contributors
Author / Creator
Doss, Prenitha Mercy Ignatius Arokia
Pereira, Resel
Fudge, Neva
Regmi, Aryan
Joly-Beauparlant, Charles
Akbar, Irshad
Yeola, Asmita Pradeep
Mailhot, Benoit
Baillargeon, Joanie
Grenier, Philippe
Bertrand, Nicolas
Lacroix, Steve
Droit, Arnaud
Moore, Craig S.
Rojas, Olga L.
Rangachari, Manu
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_03e8ecf578cd4ef3913cc229d2858241
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_03e8ecf578cd4ef3913cc229d2858241
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49259-0
