Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms
Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pannexins are single-membrane large-pore channels that release ions and ATP upon activation. Three isoforms of pannexins 1, 2, and 3, perform diverse cellular roles and differ in their pore lining residues. In this study, we report the cryo-EM structure of pannexin 3 at 3.9 Å and analyze its structural differences with pannexin isoforms 1 and 2. Th...
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Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms
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TN_cdi_doaj_primary_oai_doaj_org_article_03f0c6d8635c440587287f9c5ea0736a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_03f0c6d8635c440587287f9c5ea0736a
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-47142-6
