AMP-activated protein kinase mediates adaptation of glioblastoma cells to conditions of the tumor mi...
AMP-activated protein kinase mediates adaptation of glioblastoma cells to conditions of the tumor microenvironment
About this item
Full title
Author / Creator
Lorenz, Nadja I. , Sauer, Benedikt , Urban, Hans , Weinem, Jan-Béla , Parmar, Bhavesh S. , Zeiner, Pia S. , Strecker, Maja I. , Schulte, Dorothea , Mittelbronn, Michel , Alekseeva, Tijna , Sevenich, Lisa , Harter, Patrick N. , Münch, Christian , Steinbach, Joachim P. , Luger, Anna-Luisa , Heiland, Dieter Henrik and Ronellenfitsch, Michael W.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular metabolic activity. We hypothesized that in glioblastoma (GB), AMPK plays a pivotal role in balancing metabolism under conditions of the tumor microenvironment with fluctuating and often low nutrient and oxygen availability. Impairment of this network could thus interfe...
Alternative Titles
Full title
AMP-activated protein kinase mediates adaptation of glioblastoma cells to conditions of the tumor microenvironment
Authors, Artists and Contributors
Author / Creator
Sauer, Benedikt
Urban, Hans
Weinem, Jan-Béla
Parmar, Bhavesh S.
Zeiner, Pia S.
Strecker, Maja I.
Schulte, Dorothea
Mittelbronn, Michel
Alekseeva, Tijna
Sevenich, Lisa
Harter, Patrick N.
Münch, Christian
Steinbach, Joachim P.
Luger, Anna-Luisa
Heiland, Dieter Henrik
Ronellenfitsch, Michael W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0417806712704914abc1910aa205bd66
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0417806712704914abc1910aa205bd66
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-025-03346-2
