Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder. Increased Aβ production plays a fundamental role in the pathogenesis of the disease and BACE1, the protease that triggers the amyloidogenic processing of APP, is a key protein and a pharmacological target in AD. Changes in neuronal activity have been linked to BACE1...
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Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_0432a5c706c549658e2f87056cfe8f8a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0432a5c706c549658e2f87056cfe8f8a
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04062-3
